Housekeeping Genes. Housekeeping genes are genes that are required for the maintenance of basal cellular functions that are essential for the existence of a cell, regardless of its specific role in the tissue or organism Thus, they are expected to be expressed in all cells of an organism under normal conditions, irrespective of tissue type, developmental stage, cell cycle state, or external signal
List of the highly expressed housekeeping genes Download Scientific Diagram from www.researchgate.net
Housekeeping genes are genes that are required for the maintenance of basal cellular functions that are essential for the existence of a cell, regardless of its specific role in the tissue or organism However, the relationship between these criteria has not been much discussed
List of the highly expressed housekeeping genes Download Scientific Diagram
Thus, they are expected to be expressed in all cells of an organism under normal conditions, irrespective of tissue type, developmental stage, cell cycle state, or external signal Godbey, in An Introduction to Biotechnology, 2014 4.2.3.2.1.2 CpG Islands The TATA box is not the only feature that can be used to identify the location of the gene Some genes, however, are constitutively expressed in all tissues and their expression levels are comparatively constant across different cell types
. Some genes, however, are constitutively expressed in all tissues and their expression levels are comparatively constant across different cell types Godbey, in An Introduction to Biotechnology, 2014 4.2.3.2.1.2 CpG Islands The TATA box is not the only feature that can be used to identify the location of the gene
. Introduction Housekeeping genes are often defined as being stably expressed in all cells and conditions [1], essential [2], belong to cellular maintenance pathways [1,3-6] and be conserved [7,8] The concept of "housekeeping gene" has been used for four decades but remains loosely defined